We all remember the "Bates Motel" from Psycho and the "Maitland House" from Beetlejuice but most iconic movie houses are fabricated.
The original design for the Psycho house was inspired by Edward Hopper's "The House by the Railroad" painting, but I believe there are so many existing houses across the country with interesting design.
To this day I think this house is creepier than the original TCM house. And with the original house remodeled and turned into a restaurant, I feel the original lost some of it's Horror Movie mystique. Where as the Hewitt house in Granger, TX retains it's erie vibe down to the filthy pillars and balcony. Not to mention the creepy residents who live in this area, The Hewitt house with it's big, cold, simple design has proven to be a memorable piece of horror movie history.